Room-temperature X-ray crystallography reveals the oxidation and reactivity of cysteine residues in SARS-CoV-2 3CL Mpro: insights into enzyme mechanism and drug design
Daniel W. Kneller, Gwyndalyn Phillips, Hugh O’Neill, Kemin Tan, A. Joachimiak, Leighton Coates, Andrey Y. Kovalevsky
Journal
- ISSN / E-ISSN
- — / —
- DOI
- 10.1107/s2052252520012634 ↗
- Volume · Issue · Pages
- 7 · 6 · 1028-1035
- Publisher
- International Union of Crystallography
- Article URL
- https://doi.org/10.1107/s2052252520012634 ↗
- Article details
- Unverified
Publication date (each date has its type and source)
21 Sep 2020
OpenAlex publication date · source: OpenAlex
| Type | Date | Source |
|---|---|---|
| OpenAlex publication date | 21 Sep 2020 | OpenAlex |
Keywords (as given): SARS-CoV-2; main protease; cysteine oxidation; Cys145; N-ethylmaleimide; protease inhibitors; room-temperature X-ray crystallography
HEC Status at Publication Not the journal's current status
HEC Status at PublicationNot conclusive
Historical status could not be conclusively determined.
- HEC status cannot be determined for this date: no HEC list is recorded as in effect on it.
Best available information, not a definitive status: HEC status cannot be determined for this date: no HEC list is recorded as in effect on it.
- Journal
- IUCrJ
- Publication date used
- 21 Sep 2020 (OpenAlex publication date)
- Applicable HEC period
- None recorded for this date
- Category
- —
- Recognition status
- Unknown (NO_PERIOD_FOR_DATE)
- Source
- —
- Verification status
- Not available
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