Reasons for Failed Trials of Disease-Modifying Treatments for Alzheimer Disease and Their Contribution in Recent Research

Konstantina G. Yiannopoulou, Aikaterini Anastasiou, Venetia Zachariou, Sigliti‐Henrietta Pelidou
Journal
ISSN / E-ISSN
— / —
DOI
10.3390/biomedicines7040097 ↗
Volume · Issue · Pages
7 · 4 · 97-97
Publisher
MDPI AG
Article URL
https://doi.org/10.3390/biomedicines7040097 ↗
Article details
Unverified
Publication date (each date has its type and source)
09 Dec 2019
OpenAlex publication date · source: OpenAlex
Dates on record for this article
TypeDateSource
OpenAlex publication date09 Dec 2019 OpenAlex

Keywords (as given): Alzheimer's disease; disease-modifying therapy; clinical trial failure; drug development; prodromal Alzheimer's disease; preclinical Alzheimer's disease; biomarkers; amyloid; tau protein; neurofilament light chain; neurogranin; treatment goals; combination therapy; Bayesian analysis; clinical trial design; trial simulation

HEC Status at Publication Not the journal's current status

HEC Status at PublicationNot conclusive
Best available information, not a definitive status: HEC status cannot be determined for this date: no HEC list is recorded as in effect on it.
Journal
Biomedicines
Publication date used
09 Dec 2019 (OpenAlex publication date)
Applicable HEC period
None recorded for this date
Category
—
Recognition status
Unknown (NO_PERIOD_FOR_DATE)
Source
—
Verification status
Not available
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