E3 Ligase Ligands in Successful PROTACs: An Overview of Syntheses and Linker Attachment Points

Aleša Bricelj, Christian Steinebach, Robert D. Kuchta, Michael Gütschow, Izidor Sosič
ISSN / E-ISSN
— / —
DOI
10.3389/fchem.2021.707317 ↗
Volume · Issue · Pages
9 · — · 707317-707317
Publisher
Frontiers Media S.A.
Article URL
https://doi.org/10.3389/fchem.2021.707317 ↗
Article details
Unverified
Publication date (each date has its type and source)
05 Jul 2021
OpenAlex publication date · source: OpenAlex
Dates on record for this article
TypeDateSource
OpenAlex publication date05 Jul 2021 OpenAlex

Keywords (as given): PROTACs; bifunctional molecules; cereblon; VHL; IAP; MDM2; ubiquitination; proteasomal degradation; ternary complex formation; drug discovery

HEC Status at Publication Not the journal's current status

HEC Status at PublicationConclusive
HEC status at publication Recognized W
Based on the recorded HEC dataset applicable to the article's publication date. Listed as W in the HEC list for hjrs 2021-22 V2.
Journal
Frontiers in Chemistry
Publication date used
05 Jul 2021 (OpenAlex publication date)
Applicable HEC period
hjrs 2021-22 V2 (version 1) · 01 Jul 2021 – 30 Jun 2022
Category
W
Recognition status
Recognized (OK_RECORD_FOUND)
Source
hjrs-2021-22 row 7692
Verification status
Verified against source · last verified 16 Oct 2026
This is an automatically generated summary based on the information available on the publication date. Terms & conditions apply.